Piracetam (Nootropil)
Piracetam (Nootropil) is the best known and most widely used
Smart Drug, or Nootropic. Nootropics stimulate the central nervous system to
improve cognitive functions such as memory, attention and intelligence. What's
more, it does not contain any toxic or addictive properties.
How does Piracetam work?
Piracetam was first synthesized in 1964, and was the first of the nootropic or
cognitive enhancement drugs of its type. Although the mechanism of action
remains unknown, it has demonstrated increased blood flow and oxygen levels to
areas of the brain. It is thought to facilitate movement of information between
the brain's two hemispheres via the corpus callosum and improve the function of
receptors that are responsible for memory processes.
Piracetam has been studied in a widely in Europe on goldfish, mice, rats, guinea
pigs, rabbits, cats, dogs, marmosets, monkeys and humans. Studies illustrated
that, given intravenously to rats at 8gm/kg body weight, no toxicity was
evident. Tacconi and Wurtman stated that: "Piracetam apparently is virtually
non-toxic.... Rats treated chronically with 100 to 1,000 mg/kg orally for 6
months and dogs treated with as much as 10g/kg orally for 1 year did not show
any toxic effect .
Although there is no evidence that Piracetam has specifically addressed the
cause of Dyslexia, meta-reviews indicate that it improves performance of
cognitive tasks in dyslexic children, including:- verbal learning, as well as
speed and accuracy of reading, writing and spelling. It has also shown positive
results in treating post-stroke aphasia, epilepsy, cognitive decline (following
heart and brain surgery), dementia, and myoclonus.
Piracetam has been used successfully to treat alcoholism and alcohol withdrawal
syndrome in both man and animals, and has slowed the deterioration of 'senile
involution' dementia and Alzheimer's disease. Furthermore, it has improved
alertness, co-operation and socialization in elderly psychiatric patients
suffering from 'mild diffuse cerebral impairment.'
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